diff --git a/configure.ac b/configure.ac
index ae756038e7d..15dc41c55f9 100644
--- a/configure.ac
+++ b/configure.ac
@@ -5927,7 +5927,7 @@ LIBS="$LIB_PTHREAD $LIB_MATH $LIBS"
 AC_CHECK_FUNCS([accept4 fchdir gethostname \
 getrusage get_current_dir_name \
 lrand48 random rint tcdrain trunc \
-select getpagesize setlocale newlocale \
+select getpagesize newlocale \
 getrlimit setrlimit shutdown \
 pthread_sigmask strsignal setitimer \
 sendto recvfrom getsockname getifaddrs freeifaddrs \
diff --git a/src/emacs.c b/src/emacs.c
index d8b6da5a65a..77929817447 100644
--- a/src/emacs.c
+++ b/src/emacs.c
@@ -399,14 +399,6 @@ section of the Emacs manual or the file BUGS.\n"
 /* True if handling a fatal error already.  */
 bool fatal_error_in_progress;
 
-#if !HAVE_SETLOCALE
-static char *
-setlocale (int cat, char const *locale)
-{
-  return 0;
-}
-#endif
-
 /* True if the current system locale uses UTF-8 encoding.  */
 static bool
 using_utf8 (void)
@@ -3268,7 +3260,6 @@ You must run Emacs in batch mode in order to dump it.  */)
 #endif
 
 
-#if HAVE_SETLOCALE
 /* Recover from setlocale (LC_ALL, "").  */
 void
 fixup_locale (void)
@@ -3288,7 +3279,7 @@ synchronize_locale (int category, Lisp_Object *plocale, Lisp_Object desired_loca
       *plocale = desired_locale;
       char const *locale_string
 	= STRINGP (desired_locale) ? SSDATA (desired_locale) : "";
-# ifdef WINDOWSNT
+#ifdef WINDOWSNT
       /* Changing categories like LC_TIME usually requires specifying
 	 an encoding suitable for the new locale, but MS-Windows's
 	 'setlocale' will only switch the encoding when LC_ALL is
@@ -3297,9 +3288,9 @@ synchronize_locale (int category, Lisp_Object *plocale, Lisp_Object desired_loca
 	 numbers is unaffected.  */
       setlocale (LC_ALL, locale_string);
       fixup_locale ();
-# else	/* !WINDOWSNT */
+#else
       setlocale (category, locale_string);
-# endif	/* !WINDOWSNT */
+#endif
     }
 }
 
@@ -3313,21 +3304,20 @@ synchronize_system_time_locale (void)
 		      Vsystem_time_locale);
 }
 
-# ifdef LC_MESSAGES
+#ifdef LC_MESSAGES
 static Lisp_Object Vprevious_system_messages_locale;
-# endif
+#endif
 
 /* Set system messages locale to match Vsystem_messages_locale, if
    possible.  */
 void
 synchronize_system_messages_locale (void)
 {
-# ifdef LC_MESSAGES
+#ifdef LC_MESSAGES
   synchronize_locale (LC_MESSAGES, &Vprevious_system_messages_locale,
 		      Vsystem_messages_locale);
-# endif
+#endif
 }
-#endif /* HAVE_SETLOCALE */
 
 /* Return a diagnostic string for ERROR_NUMBER, in the wording
    and encoding appropriate for the current locale.  */
diff --git a/src/lisp.h b/src/lisp.h
index 59d8e497f13..68b77a88aa7 100644
--- a/src/lisp.h
+++ b/src/lisp.h
@@ -5190,15 +5190,9 @@ extern AVOID terminate_due_to_signal (int, int);
 #ifdef WINDOWSNT
 extern Lisp_Object Vlibrary_cache;
 #endif
-#if HAVE_SETLOCALE
 void fixup_locale (void);
 void synchronize_system_messages_locale (void);
 void synchronize_system_time_locale (void);
-#else
-INLINE void fixup_locale (void) {}
-INLINE void synchronize_system_messages_locale (void) {}
-INLINE void synchronize_system_time_locale (void) {}
-#endif
 extern char *emacs_strerror (int) ATTRIBUTE_RETURNS_NONNULL;
 extern void shut_down_emacs (int, Lisp_Object);
 
diff --git a/src/sysdep.c b/src/sysdep.c
index 9e4f3b211bb..089fc74deb8 100644
--- a/src/sysdep.c
+++ b/src/sysdep.c
@@ -4593,15 +4593,11 @@ freelocale (locale_t loc)
 static char *
 emacs_setlocale (int category, char const *locale)
 {
-#  ifdef HAVE_SETLOCALE
   errno = 0;
   char *loc = setlocale (category, locale);
   if (loc || errno)
     return loc;
   errno = EINVAL;
-#  else
-  errno = ENOTSUP;
-#  endif
   return 0;
 }